Searchable abstracts of presentations at key conferences in endocrinology

ea0038p189 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

The effect of L-arginine on anorectic gut hormone release in humans

Amin Anjali , Neophytou Christina , Murphy Kevin

High protein diets suppress appetite and facilitate weight loss, but are difficult to adhere to in the long-term. Understanding the mechanisms by which protein suppresses appetite may establish targets for more acceptable interventions to treat or prevent obesity. Of particular interest is the concept of functional foods or novel products which aim to potentiate satiety. However, the specific mechanisms regulating protein-induced satiety are unknown. Protein has a satiating ef...

ea0034p42 | Clinical biochemistry | SFEBES2014

Urinary 3-methoxytyramine as a biomarker of phaeochromocytoma and paraganglioma tumours

Neophytou Christina , Darch Sarah , Gill Jasdeep Singh , Hancock Maggie , Meeran Karim , Palazzo Fausto , Tan Tricia

Phaeochromocytomas (PCC) and paragangliomas (PGL) are rare tumours derived from the sympathetic or parasympathetic paraganglia. They characteristically secrete catecholamines (noradrenaline/adrenaline/dopamine), which are metabolised to the metanephrines (normetadrenaline/metadrenaline/3-MT respectively). These tumour markers can be detected in acidified 24-h urine collections as first-line investigative tests. Plasma 3-MT has been characterised as a biomarker of metastatic PG...