Endocrine Abstracts

Background: De Quervain’s thyroiditis is a transient inflammatory thyroid disorder, characterized by neck pain, a tender goiter and a triphasic clinical course of thyroid function evolution.Clinical Case: A 21-year-old male presented to the emergency department with 5 days of fever, agitation, palpitations, diarrhea and cough. He had a significant past medical history of aplastic anemia, in remission after an allogeneic stem cell transplant a year a...

Tumour-Induced Osteomalacia (TIO) is a rare paraneoplastic syndrome that is often underdiagnosed given its non-specific manifestations. A 64-year-old Chinese male presented with chest discomfort and generalized weakness. He was treated for symptomatic iron deficiency anaemia, with two units of blood transfusion given his low haemoglobin of 6.1 g/dl; no intravenous iron replacement was given. Concurrently, laboratory results revealed a low phosphate level of 0.4 mmol/l [referen...

Background: Severe hypercortisolism from ectopic adrenocorticotropic (ACTH) secretion may be life-threatening. The lung is the most common site of ACTH secreting tumours, ranging from bronchial carcinoids to small cell lung carcinoma. Olfactory neuroblastomas (ONB) are rare malignant neuroectodermal tumours. They show neuroendocrine differentiation and may exhibit a wide variety of paraneoplastic syndromes including ectopic ACTH secretion (EAS). We report a case of EAS from a ...