Endocrine Abstracts

Case history: Two Syrian refugee siblings aged 21 and 20 years, were referred. Ambiguous genitalia had been identified at birth and had been raised as males. They wished a more masculine habitus and had concerns regarding their fertility. The elder sibling had ambiguous genitalia at birth and a 46,XX karyotype. Long-term steroid treatment had been initiated and corrective genital surgery performed at 9 months of age. For unknown reasons, steroids were stopped after 9 years. He...

Introduction: Cushing’s disease is usually caused by functional corticotroph microadenomas of the pituitary. Crooke’s cell adenomas are rare, representing approximately 2% of corticotroph adenomas and mostly present as aggressive macroadenomas. Pituitary adenomas showing immunoreactivity for both ACTH and GH are also very uncommon. We present two cases of Cushing’s disease caused by macroadenomas with Crooke’s cell cha...

Introduction: Cushing’s disease is usually caused by functional corticotroph microadenomas of the pituitary. Crooke’s cell adenomas are rare, representing approximately 2% of corticotroph adenomas and mostly present as aggressive macroadenomas. Pituitary adenomas showing immunoreactivity for both ACTH and GH are also very uncommon. We present two cases of Cushing’s disease caused by macroadenomas with Crooke’s cell cha...

Introduction: Obesity represents a major public health challenge and is linked with increased risk of multiple medical conditions including atrial fibrillation (AF). We have recently published the study protocol of the ‘The Effect of complex weigHt-reducing interventiOns on rhythm control in oBese subjects wITh Atrial Fibrillation’ (HOBIT-AF) trial. Here we communicate the preliminary results with the focus on the use of smart technologies and telemedicine.<...