Endocrine Abstracts

The analogues of GLP-1(aGLP1) are a new class of anti-diabetic agents, administered subcutaneously for the treatment of Diabetes Mellitus type 2 (DM2). In the Portuguese market, there are two aGLP1 currently available: Liraglutide (once-daily administration) and Exenatide (once-weekly administration). They mimic the GLP-1, produced in the small intestine, stimulated by foods at this region, increasing the production of insulin, decreasing the satiety and slowing gastric emptyi...

Introduction: The immune checkpoint inhibitors (ICI) are increasingly being used in the treatment of several malignancies. ICI are monoclonal antibodies that inhibit immune checkpoints, thus stimulating the action of the immune cells to attack the tumour cells. The overstimulation of the immune system can lead to several endocrinopathies, such as autoimmune diabetes, known as ICI-associated diabetes mellitus (ICIDM).Case Report: In September 2023, a 62-y...