Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1079 | Pituitary - Clinical | ECE2017

Cushing syndrome and pregnancy: a systematic review including three new cases

China Diogo , Oliveira Ana Isabel , Belo Sandra , Carvalho Davide

Cushing’s Syndrome (CS) is an uncommon disease worldwide, being characterized by an increased production of glucocorticoids, and if left untreated can lead to serious consequences and women with CS rarely get pregnant. The aim of our work is to make a systematic review of the cases of pregnancy in patients with previously diagnosed CS, being performed an extensive research of the Medline and Web of Knowledge databases, and add three new cases observed in our institution. ...

ea0040p16 | (1) | ESEBEC2016

Insulinomas at São João Hospital between 1980 and 2015

Neves Joao Sergio , Lau Eva , Oliveira Joana , Oliveira Ana Isabel , Freitas Paula , Carvalho Davide

Introduction: Insulinomas are pancreatic endocrine tumors originating in the beta cells, characterized by hypoglycemia resulting from insulin hypersecretion.Objectives: To characterize the demography, the clinical features, imagiological findings and pathological evaluation of the cases of insulinomas identified in the previous 35 years at São João Hospital.Methods: We retrospectively analyzed the cases diagnosed as insul...

ea0037ep770 | Pituitary: clinical | ECE2015

Sex-related differences in clinical presentation and outcomes of Cushing's disease: a study from a referral centre

Lau Eva , Oliveira Joana , Belo Sandra , Freitas Paula , Oliveira Ana Isabel , Vinha Eduardo , Castro Ligia , Pereira Josue , Carvalho Davide

Introduction: Cushing’s disease (CD) presents a marked female preponderance, with a female-to-male ratio of 3–8:1, but whether this skewed gender distribution has any relevance to the presentation and outcomes of CD is not well understood.Aim: To evaluate sex-related differences in the presentation of CD, as regards: biochemical indices of hypercortisolism; complications of disease and outcomes.Methods: Observational, ret...

ea0049ep53 | Adrenal cortex (to include Cushing's) | ECE2017

Adrenal cushing’s syndrome surprisingly unveiling breast cancer

Neves Joao Sergio , Oliveira Ana Isabel , Souteiro Pedro , Oliveira Sofia Castro , Baldaia Helena , Melo Daniel , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Cushing’s syndrome is an endocrinopathy characterized by glucocorticoids excess. Adrenalectomy is the recommend treatment for unilateral adrenal Cushing’s syndrome and is usually associated with resolution of the disease.Clinical Case: A 54-year old woman with central obesity (BMI 34.3 kg/m2), diabetes and hypertension had a left adrenal mass of 15 mm and characteristics suggestive of adenoma (Hounsfield unit of <10...

ea0049ep54 | Adrenal cortex (to include Cushing's) | ECE2017

Giant adrenal tumor in a patient admitted for fever

Neves Joao Sergio , Teles Luis , Souteiro Pedro , Oliveira Sofia Castro , Oliveira Ana Isabel , Fernandes Ana Catarina , Damasceno Margarida , Graca Luisa , Rodrigues Elisabete , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Adrenal tumors are usually detected due to clinical manifestations of hormonal hypersecretion or incidental findings on imaging evaluation. Although most incidentalomas are non-functioning adenomas, it is important to appropriately evaluate such masses to exclude hormonal excess or malignancy.Case description: An 81-year old male was admitted to our hospital for fever with 15 days of evolution. The patient also presented chills and loss of ...

ea0056oc1.5 | Benign thyroid diseases | ECE2018

Low free T3 levels within the reference range independently predict cardiovascular mortality in the general population

Neves Joao Sergio , Dias Catarina Viegas , Leitao Lia , Vieira Miguel Bigotte , Magrico Rita , Oliveira Ana Isabel , Falcao-Pires Ines , Lourenco Andre , Carvalho Davide , Leite-Moreira Adelino

Introduction: Several studies have suggested an association of thyrotropin (TSH) and free thyroxine (FT4) levels within the reference range with morbidity and mortality in the general population. Low free triiodothyronine (FT3) has also been associated with a poor prognosis in several conditions. However, the association between FT3 levels within the reference range and the risk of mortality in the general population remains uncertain.Methods: We evaluat...