Searchable abstracts of presentations at key conferences in endocrinology

ea0026p484 | Thyroid cancer | ECE2011

Seventh UICC/TNM staging criteria for medullary thyroid carcinoma: is there any prognostic advantage?

Martinho M , Azevedo T , Carrilho F , Martins T , Ribeiro C , Melo M , Cunha N , Rascao M J , Neves A , Gilde P , Pires J L , Cruz C , Oliveira C , Neto J , Oliveira S , Valido F , Gomes I , Carvalheiro M , Rodrigues F

Background and aims: The value of the revised (2009) UICC/TNM criteria for medullary thyroid cancer (MTC) is not established. We aimed to evaluate its predictive value, analyzing the consequences of the inclusion of T3N0M0 patients previously included in stage III of the 6th edition, in stage II of the 7th.Patients and methods: We retrospectively analysed the clinical records of 85 patients operated for MTC and followed in two tertiary hospitals in the c...

ea0029p412 | Clinical case reports - Thyroid/Others | ICEECE2012

Pseudo malabsorption of levothyroxine

Alves M. , Rodrigues D. , Baptista C. , Ribeiro C. , Oliveira P. , Vieira A. , Gouveia S. , Saraiva J. , Moreno C. , Bastos M. , Carvalheiro M.

Background: Therapy with levothyroxine (L-T4) is essential in hypothyroidism treatment. The marked elevation of thyrotropin (TSH) in patients treated with appropriate doses of L-T4 is rare and can result from malabsorption, drug interaction or poor adherence. The non-adherence, omitted by the patient, is called pseudo malabsorption.Clinical report: ACCS, female, 30 years old, hospitalized for persistent...

ea0020p231 | Bone/Calcium | ECE2009

Bone and mineral metabolism before and after kidney–pancreas transplantation in patients with type 1 diabetes

Vaz Daniel , Martins L , Dias L , Henriques C , Oliveira F , Seca R , Lhamas A , Esteves S , Ribeiro A , Almeida R , Teixeira M , Dores J

Aims: End stage renal disease is associated with disorders of calcium and phosphate metabolism that favor the loss of bone mass.Kidney transplant may alter this unbalance restoring bone mass. Nevertheless, recent studies showed that 48 months after transplant, the loss of bone mass still is superior to general population. Post-transplant corticosteroid therapy is considered the main responsible for the loss of bone mass.The authors...

ea0049gp178 | Pituitary | ECE2017

Sleep patterns in patients with non-functional GHRH receptor

Oliveira Francielle T , Salvatori Roberto , Marcondes Jose , Macena Larissa B , Oliveira-Santos Alecia A , Faro Augusto C N , Campos Viviane C , Oliveira Carla R P , Costa Ursula M M , Aguiar-Oliveira Manuel H

Hypothalamic GH releasing hormone (GHRH) has hypnotic actions by increasing slow wave sleep (SWS) (non-rapid eye movement sleep, non-REM), which account for about 75% of sleep. Conversely, GH may stimulate the rapid eye movement sleep (REM). Patients with GH deficiency (GHD) often exhibit sleep problems leading to daytime fatigue and reduced quality of life (QoL). We have described a cohort of patients with isolated GHD (IGHD) due to GHRH resistance caused by a homozygous null...

ea0026p485 | Thyroid cancer | ECE2011

Very low-risk papillary thyroid carcinoma: where to set the limits?

Martinho M , Azevedo T , Martins T , Cunha N , Rascao M J , Oliveira C , Neto J , Oliveira S , Gilde P , Neves A , Gomes I , Cruz C , Valido F , Campos B , Rodrigues F

Currently there is no widely accepted definition of very low-risk papillary thyroid carcinoma (PTC). Although unifocal microcarcinomas without extrathyroidal extension and no local or distant metastases have been recognized as having an excellent overall prognosis the threshold for such a favourable clinical behaviour remains controversial. The study aim was to identify the clinicopathological characteristics of T1 tumours (≤2 cm) presenting a very low-risk of mortality ...