Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep475 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

‘Metabolic endotoxemia’ in the presence and absence of type 2 diabetes mellitus

Egshatyan Lilit , Tkacheva Olga , Boytsov Sergey , Osipov Georgy

Background: Type 2 diabetes mellitus (T2DM) is a condition of multi-factorial origin, involving several molecular mechanisms related to the intestinal micro-biota for its development. The micro-biota able to favor systemic exposure to the lipopolysaccharides (LPS), large glycolipids derived from the outer membrane of Gram-negative bacteria. LPS can cause a condition of ‘metabolic endotoxemia’ characterized by low-grade inflammation, insulin resistance.<p class="a...