Searchable abstracts of presentations at key conferences in endocrinology

ea0081p537 | Adrenal and Cardiovascular Endocrinology | ECE2022

Management of persistent subclinical hypercortisolism post left adrenalectomy in a patient with primary bilateral macronodular adrenal hyperplasia with aberrant receptors

Moustaki Melpomeni , Papadimitriou Kasiani , Papanikolaou Vasiliki , Cherolidi Eleni , Rigana Maria , Kyriakopoulos Georgios , Kalogeris Nikolaos , Vryonidou Andromahi

Introduction: Endogenous subclinical hypercortisolism occurs in 5-30% of patients with adrenal incidentalomas. Adrenal adenoma is the commonest cause of autonomous cortisol secretion (ACS), while primary bilateral macronodular adrenal hyperplasia (PBMAH) is rare. In both, ACS results from activation of the cAMP/PKA pathway. This may be triggered by ligands, other than ACTH, acting upon aberrant G-protein coupled receptors (GPCRs), which may also control locally produced ACTH i...

ea0081p723 | Thyroid | ECE2022

Metastatic papillary thyroid carcinoma without identifiable primary tumor in a patient with IgG4-related thyroiditis: challenging diagnosis and management of a rare case

Papadimitriou Kasiani , Moustaki Melpomeni′ , Tsitsimpis Anastasios , Papanikola Nektaria , Dermentzoglou Alexandros , Spanou Loukia , Vryonidou Andromahi

Introduction: IgG4-related thyroiditis (IgG4-RTD) is a rare fibroinflammatory disorder. It is characterized by dense lymphocyte infiltration (mainly IgG4+ plasma cells), enlargement and dysfunction of the thyroid gland. IgG4-RTD includes mostly cases of Hashimoto’s (HT) but also of Riedel’s and Graves’ thyroiditis. Diagnosis is set according to imaging and histopathological criteria. Papillary thyroid carcinoma (PTC) is the most common form of thyroid cancer (~9...