Endocrine Abstracts

Introduction: A mutation in the PROP-1 gene is a rare cause of childhood-onset hypopituitarism. Patients with the disorder usually present with multiple pituitary hormone deficits. The pattern of development and the course of insufficiencies of individual axes remain unclear and affect patients metabolic status. Growth hormone therapy and substitution of other hormones may influence on glucose and lipid metabolism as well. Aim: To characterize the carboh...

Background: Despite increased awareness among cardiologists about the risk of amiodarone’s significant side effects, it is still a commonly used antiarrhythmic drug. Amiodarone may induced easy for management hypothyroidism which affect even 25% of patients or less frequent thyrotoxicosis (AIT) which causes a challenge for clinicians. Type 1 of AIT occurs on the basis of pre-existing thyroid diseases such as nodular goiter or latent Graves’ disease, type 2 results fr...