Searchable abstracts of presentations at key conferences in endocrinology

ea0066p23 | Diabetes 1 | BSPED2019

Different financial models employed by diabetes transition units within Yorkshire and South West London’s Children and Young People’s (CYP) networks

Tseretopoulou Xanthippi , Wei Christina , Peacock Amanda

Introduction: The ultimate goal of a diabetes transition service is to provide coordinated, uninterrupted and developmentally appropriate healthcare, which promotes skills in decision-making, communication, autonomy, and self-care, with an essential component required to achieve this, being adequate resourcing.Methods: Data from Yorkshire and South West London CYP diabetes networks were collected via questionnaire. The primary focus was to ascertain whic...

ea0058p022 | Growth | BSPED2018

You are what you eat: gonadotrophin independent precocious puberty

Jackson Charlotte , Peacock Amanda , Mushtaq Talat , Chowdhury Nazma , Wei Christina

Introduction: Phytoestrogens are derived from plants that are structurally and functionally similar to oestrogens. Their health benefits are widely extolled, although excessive consumption in children may cause adverse effects.Case 1: A 5.7-year old female presented with a one-month history of breast development and a 3-day history of vaginal bleeding. Prior to presentation, she was taking a health drink containing fennel and sesame seeds, in addition to...

ea0030oc2.4 | Oral Communications 2 | BSPED2012

Prenatal dexamethasone for treatment of congenital adrenal hyperplasia: a possible association with late gestational fetal demise in two cases

Peacock Amanda , Abbey Ianthe , Alvi Sabah , Bennett Chris , Dwyer James , Glanville Tracey , Mushtaq Talat

Introduction: The prenatal treatment of Congenital Adrenal Hyperplasia (CAH) with Dexamethasone (Dex) is effective at minimising virilisation in affected females. Treatment is initiated with Dex at 20 mcg/kg per day (max 1.5 mg/day) as soon as pregnancy is confirmed and continued to term in affected females only. There are concerns regarding neurocognitive difficulties in children exposed to prenatal Dex, but no reports of late intra-uterine deaths (IUD) attributed to prenatal...

ea0045p15 | Diabetes | BSPED2016

Severe acute renal failure requiring dialysis in children with diabetic ketoacidosis

Paraskevopoulou Evagelia , Peacock Amanda , Patel Leena , Burren Christine , Yong James , Bain Murray , Wei Christina

Introduction: Acute renal failure (ARF) is a rare but life-threatening complication of severe diabetic ketoacidosis (DKA) in children.Aim: To characterise the presentation, treatment and clinical course of children with DKA complicated by severe ARF requiring renal support.Method: Retrospective notes review of patients aged <16 years admitted in 2011–2016 to 3 UK regional paediatric intensive care units (St George’s H...

ea0045p35 | Diabetes | BSPED2016

Assessing the impact of a youth worker on diabetes care in adolescents with type 1 diabetes

Peacock Amanda , Guest Matthew , Cropper Julie , Trentham Sarah , Clarke Michelle , Yong James , Campbell Fiona

Background: The inclusion of a youth worker within a transition service can be pivotal to its success.Objective: To assess the impact of a youth worker on diabetes care in adolescents with type 1 diabetes (T1DM) over a 6 month period by measuring HbA1c levels (primary outcome), Personal Development Tool score (PDT), hospital admissions and clinic attendance (secondary outcomes).Method: Prospective cohort study. 20 adolescents (age ...

ea0039oc9.2 | Oral Communications 9 | BSPED2015

Identifying critical periods for maintaining weight loss in obese children

Peacock Amanda , Mushtaq Talat , Alexander Erin , Truby Helen , Greenwood Darren , Russo Vince , Yau Steven , Werther George , Sabin Matthew

Background: Studies in adults have shown physiological protection of a ‘set-point’ for weight, explaining why obese adults who diet eventually regain weight.Objective: We hypothesised that set-points for weight, and their physiological defence, are flexible in childhood but become fixed around puberty. We aimed to show that obese children who lost weight had less ‘reflex’ changes in satiety hormone profiles (that would drive weight re...

ea0045oc8.4 | Oral Communications 8- Diabetes | BSPED2016

Effect of weight loss on Resting Energy Expenditure in pre- and post-pubertal obese children

Peacock Amanda , Mushtaq Talat , Alexander Erin , Truby Helen , Greenwood Darren , Russo Vince , Yau Steven , Werther George , Sabin Matthew

Background: In obese adults, caloric restriction leads to a reduction in energy expenditure, and it is this compensatory adaptive down-regulation that is cited as one of the causes of weight regain in adults. There are currently insufficient data to establish if this phenomenon also occurs in obese children who lose weight and whether puberty affects this adaptive response.Objective: We hypothesised that obese children who lose weight have less ‘ref...