Searchable abstracts of presentations at key conferences in endocrinology

ea0029p379 | Clinical case reports - Pituitary/Adrenal | ICEECE2012

Acromegaly, primary hyperparathyroidism and renal cell carcinoma

Nogueira C. , Vinha E. , Mesquita J. , Belo S. , Capela J. , Pereira J. , Coutinho H. , Castro L. , Souto-Moura C. , Resende A. , Bernardes I. , Carvalho D.

Introduction: Acromegaly is a rare disorder and sporadic cases are the most frequent. It can also occur in association with genetic syndromes, such as Carney complex, multiple endocrine neoplasia type 1 (MEN-1), MEN-1 like syndrome, isolated familial acromegaly and familial isolated pituitary adenomas.Case report: Thirty five -year-old man was observed in 1994 for gynecomastia. Acromegaly was diagnosed based on clinical, biochemical (IGF1 1094.7 ng/ml, b...

ea0040p8 | (1) | ESEBEC2016

Medullary thyroid cancer in a RET-negative patient with a germline SDHB mutation

Simoes-Pereira J , Leite V

Introduction: Medullary thyroid cancer (MTC), in its familial forms, is usually associated with pheochromocytoma and primary hyperparathyroidism, related to an underlying germline RET mutation. SDHx germline mutations associated with MTC have not yet been reported.Case report: We report the case of a 60-years-old woman, who was submitted, elsewhere, in November/2013, to a total thyroidectomy+right lymph-node dissection due to a nodule s...

ea0035p53 | Adrenal cortex | ECE2014

Clinical characteristics and follow-up of patients with adrenal incidentalomas

Fernandes Vera , Santos Maria J , Pereira Maria L , Alves Marta , Souto Selma , Marques Olinda

Background: The adrenal incidentalomas (AI), adrenal masses ≥10 mm in diameter incidentally detected, have increased their prevalence due to technological advances in imaging. The adrenalectomy is indicated in functioning adrenal tumors and in cases suspected of malignancy.Objectives: To analyze the characteristics of patients with AI and to evaluate the clinical outcome, in terms of evolution toward hypersecretion and significant growth, during fo...

ea0029p1363 | Pituitary Clinical | ICEECE2012

Familial isolated pituitary adenoma: review of four families

Belo S. , Mesquita J. , Nogueira C. , Magalhaes A. , Basto M. , Pereira J. , Carvalho D.

Introduction: Pituitary adenomas are frequent brain tumors, with prevalence of about 1:1000. Most occur sporadically. The familial forms represent 5% of cases. These can be found associated with other endocrine neoplasia (MEN 1, Carney complex, MEN 4) or as a clinical isolated entity – FIPA. This is characterized by the presence of pituitary tumors in two or more family members, in the absence of features of other endocrine syndromes. AIP gene mutation, which may or may n...

ea0029p1453 | Pituitary Clinical | ICEECE2012

Pituitary dysfunction in adult patients after cranial radiotherapy for non-pituitary tumors: a long-term follow-up study

Appelman-Dijkstra N. , Kokshoorn N. , Malgo F. , Neelis K. , Biermasz N. , Smit J. , Pereira A.

Background: Hypopituitarism after cranial radiotherapy for non-pituitary tumors is well recognized. However structured endocrine assessments are not incorporated into routine clinical practiceAim of the study: To evaluate pituitary function in adult patients irradiated for non-pituitary tumors at our centerPatients and Methods: Cross-sectional evaluation of pituitary function of all available patients treated with irradiation at ou...

ea0026p642 | Clinical case reports | ECE2011

Giant invasive macroprolactinoma

Alves M , Neves C , Pereira J , Bastos M Ayres , Bernardes I , Carvalho-Braga D , Carvalho D

Background: Apart from signs of hyperprolactinaemia, patients with macroadenomas with extrasellar extension generally seek medical attention due to mass effect. Macroprolactinomas, particularly in men, may occasionally exhibit a very aggressive clinical course.Case report: Male 37 years old that went to a Neurology consultation complaining of progressively more frequent self-limiting episodes of restraint, silence and time and space disorientation in the...

ea0011p211 | Comparative endocrinology | ECE2006

The patients with HIV lipodystrophy syndrome have lower total fat mass but similar free fat mass

Freitas P , Carvalho D , Correia F , Faria T , Perez B , Marques R , Serrão R , Pereira J , Mota Miranda A , Medina JL

Introduction: The highly active antiretroviral therapy (HAART) completely changed the natural history and body composition of the infected patients. The lipodystrophy syndrome of HIV-infected patients (IP) is characterized by fat mass redistribution in the limbs, face lipoatrophy and abdominal lipohypertrophy. Dual-energy x-ray absorptiometry scan (DEXA) and bioelectrical impedance (BIA) are techniques to determine body composition (BC).Aims: Evaluate th...