Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep683 | Pituitary and Neuroendocrinology | ECE2022

Pituitary Coma? Discordant pituitary biochemistry after consumption of a commercially available ‘Sleep Activator’.

Phillips Benjamin , Kumar Mohit

We present a case of discordant pituitary biochemistry which resolved after discontinuing a commercially available combination vitamin supplement. A 35 year-old man presented following an episode of headache and dizziness, preceding collapse and possible seizure activity. Investigations revealed deranged pituitary function: TSH 0.02 mU/l (0.35-5.50), fT4 3.6 pmol/l (10.0-20.0), 9 am cortisol 18 nmol/l (200-500), testosterone >52 nmol/l (8.4-28.7), FSH <0.3 U/l (1.0-18....

ea0094cc5 | Section | SFEBES2023

A case of an ACTH-secreting phaeochromocytoma: Biochemical response to metyrapone suggests the presence of a glucocorticoid-driven positive feedback loop

Michaelidou Maria , Phillips Benjamin , Man Mung Sai , Al-Hayali Mohammed , Chen Lilian , Allcock Rebecca , Monaghan Phillip , Thirkettle Sally , Clarke Noel , Gulamhusein Aziz , Beards Sue , Hoong Ho Jan , Kaushal Kalpana , Howell Simon , Adam Safwaan

Phaeochromocytoma-driven Ectopic ACTH Syndrome (EAS) is rare. We report the case of a 31-year-old female, who presented with abdominal pain and vomiting. She had clinical features of severe Cushing’s syndrome (proximal myopathy, bruising, refractory hypertension and acute confusion). Admission investigations revealed hypokalaemia (2.1mmol/l [3.5-5.5mmol/l]) and a 4.5cm left adrenal lesion with a ’bulky’ right adrenal on CT abdomen. She was diagnosed with hyperte...