Searchable abstracts of presentations at key conferences in endocrinology

ea0019p79 | Clinical practice/governance and case reports | SFEBES2009

Directly observed medication supplementation for non-compliance in a patient with hypothyroidism and hypoparathyroidism

Pickett P , Iqbal R , Mundinamani D , Macleod A , Moulik P

Introduction: Hypocalcemia in post-operative hypoparathyroidism responds to oral vitamin D and calcium replacement. We describe a case of persistent symptomatic hypocalcemia and hypothyroidism despite oral replacement and management with supervised weekly supplementation.Case history: A 56-year-old lady had total thyroidectomy for multinodular goitre. Persistent post-operative hypoparathyroidism and hypothyroidism necessitated replacement with calcitriol...

ea0013p46 | Clinical practice/governance and case reports | SFEBES2007

Drug-induced symptomatic hypomagnesaemia and hypocalcaemia

Tahrani AA , Rangan S , Pickett P , Macleod AF , Moulik PK

Hypomagnesaemia can cause Hypocalcaemia as magnesium interferes with parathyroid hormone action and secretion. It also causes hypokalemia due to defective membrane ATPase or urinary potassium loss. We present two patients who were admitted to our hospital with symptoms and signs of hypocalcaemia secondary to drug-induced hypomagnesaemia and describe the lessons learned.Patient 1: A 46 year-old lady presented with “pins and needles” and muscle c...

ea0013p70 | Clinical practice/governance and case reports | SFEBES2007

Serum prolactin normalisation does not always predict tumour shrinkage in prolactinomas: A case report.

Tahrani AA , Rangan S , Pickett P , Macleod AF , Moulik PK

Prolactinomas are the most common pituitary adenomas. The treatment is primarily medical with dopamine agonists. The improvements in prolactin levels are accompanied by reduction in the tumour size in the majority of cases. We report a patient with a macroprolactinoma whose tumour enlarged despite achieving normal prolactin levels.A 55-year-old gentleman was referred to the ophthalmologist with worsening vision in the left eye. Clinical examination revea...

ea0012p14 | Clinical case reports/Governance | SFE2006

Hirsuitism and amenorrhoea – not always “PCOS”

Rangan S , Tahrani AA , Siddique H , Pickett P , Moulik PK

Polycystic ovarian syndrome (PCOS) is a common disorder affecting women of childbearing age. The clinical triad of PCOS includes: hirsuitism, oligo/amenorrhoea and ultrasonographic appearances of PCOS. However, this triad could occur in other disorders such as late onset congenital adrenal hyperplasia (CAH). Although CAH is mainly diagnosed in childhood, it could occur in adults. In this abstract we describe a patient who presented with features of PCOS, the final diagnosis, h...

ea0012p15 | Clinical case reports/Governance | SFE2006

Once weekly thyroxine as a treatment strategy in non-compliant hypothyroid patients

Rangan S , Tahrani AA , Pickett P , Macleod AF , Moulik PK

Once daily Thyroxine is the treatment of choice for hypothyroidism. The dose of Thyroxine needed varies with a mean of 1.6 mcg/kg bodyweight a day. The most common cause for requiring larger doses is non-compliance although other causes such as malabsorption and drugs should be excluded. In this abstract we describe two patients with hypothyroidism that required large doses of thyroxine secondary to poor compliance in which supervised once weekly thyroxine therap...

ea0013p309 | Thyroid | SFEBES2007

An audit of radio active iodine treatment in the management of thyrotoxicosis at a district general hospital

Rangan S , Tahrani AA , Ghosh D , Pickett P , Macleod AF , Moulik PK

Aim: To audit radioactive iodine (RAI) treatment.Methods : A retrospective audit of thyrotoxic patients, who attended the one-stop RAI clinic, between April 2005 and February 2006.Results: We included 74 patients (60 females, 14 males) with a median age 54 (22–85) years.Before RAI: Smoking history was recorded in 19/74(26%) patients. 44/74(59%) patients received drug treatment for two years or mor...