Endocrine Abstracts

We present two cases of rare connective tissue disease precipitated by antithyroid medication. The first case is a 37-year-old woman from the Philippines who presented with thyrotoxicosis. She was commenced on Carbimazole, which was subsequently switched to propylthiouracil, as she wanted to become pregnant without delay. Within 2 months she had developed Raynaud’s phenomenon and a facial rash. Autoantibody testing showed a positive ANA of speckled pattern, negative doubl...

Background: Bruns Garlands syndrome is a rare disorder in people living with diabetes, manifesting as unilateral or bilateral muscle pain, weakness and atrophy in the proximal region of the lower limbs. Herein, we present the case of a patient with Bruns-Garland syndrome caused by sodium/glucose co-transporter 2 inhibitors (SGLT2i).Case description: A 55-year-old male with background of type 2 diabetes for 5 years, and currently on oral therapy, presente...

Background: Bruns Garlands syndrome is a rare disorder in people living with diabetes, manifesting as unilateral or bilateral muscle pain, weakness and atrophy in the proximal region of the lower limbs. Herein, we present the case of a patient with Bruns-Garland syndrome caused by sodium/glucose co-transporter 2 inhibitors (SGLT2i).Case description: A 55-year-old male with background of type 2 diabetes for 5 years, and currently on oral therapy, presente...

A 34-year-old Caucasian male with type 1 diabetes, diabetic nephropathy and secondary hyperparathyroidism was electively admitted for parathyroidectomy. He is on regular peritoneal dialysis and is on the renal transplant list.On admission his PTH was 215.3 and corrected calcium was 2.01. Other biochemical parameters remained stable. He uneventfully underwent a total parathyroidectomy. No implantation of any of the parathyroid glands was done. He did not ...

Background: There is controversy about the ideal outcome for radio-active iodine (RAI) treatment in thyrotoxicosis and the optimal dose to be given. Various centres use various doses ranging from 185 mBq to 550 mBq.Aim: Our aim was to determine the thyroid status post RAI treatment for thyrotoxicosis and in those who became hypothyroid, to assess the time of onset of hypothyroidism from the date of RAI treatment administration.Meth...

Both diabetes and Addisons’ are conditions which can be associated with muscle weakness and altered potassium levels. This is a case of recurrent muscle paralysis in a patient with both conditions with the underlying abnormality being the neurological condition of hypokalaemic periodic paralysis.A 23-year-old Caucasian gentleman was admitted to medical admissions with sudden onset weakness of his lower legs. On examination he had reduced power of hi...