Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1018 | Pituitary - Clinical | ECE2017

Disposition index in active acromegaly: A pilot study

Niculescu Dan Alexandru , Dusceac Roxana , Caragheorgheopol Andra , Popescu Nicoleta , Poiana Catalina

Background: Active acromegaly is characterized by decreased insulin sensitivity (ISen). However, insulin secretion (ISec) may not increase satisfactorily to compensate for the low ISen.Aim: To assess ISen and ISec and to calculate disposition index (DI) using an intravenous glucose tolerance test (IVGTT) in patients with active acromegaly.Methods: Twelve patients (7 men, 5 women) with active acromegaly and 2 normal subjects (2 men)...

ea0056ep113 | Pituitary and Neuroendocrinology | ECE2018

Serum concentration of insulin-like growth factor I (IGF-I): reference values for adult Romanian population: Preliminary results

Alexandru Niculescu Dan , Dobre Ramona , Caragheorgheopol Andra , Popescu Nicoleta , Poiana Catalina

Background: Growth hormone, age, sex, genetics or nutrition status play an important role in insuline-like growth factor 1 (IGF-1) liver production and serum levels. Currently, there is no IGF-I reference range for Romanian population.Aim: To define sex- and age-adjusted reference values for serum IGF-I measured by an automated chemiluminescence immunoassay in adult Romanian population of healthy subjects.Methods: The study include...