Endocrine Abstracts

Introduction: Metastatic thyroid tumors are infrequent, accounting for just 3% of all thyroid cancers. Interestingly, 7.8% of these metastases stem from breast cancer. Previous malignancies increase metastatic suspicions when thyroid nodules, possibly accompanied by cervical lymphadenopathy, are discovered. As our case emphasizes, diagnostics can be complex, necessitating specialized treatment and monitoring plans.Case Presentation: A 55-year-old female ...

Introduction: Acromegaly is a progressive disorder caused by excess growth hormone (GH), usually due to a GH-secreting pituitary adenoma, associated with an increased risk of cancer-related mortality. Insulin-like growth factor 1 (IGF-1) has been involved in tumor development by promoting cell proliferation and inhibiting apoptosis. Multiple myeloma (MM), a plasma cell neoplasm, has been suggested to have a potential link to IGF-1 in its pathogenesis.Cas...

Introduction: Recent studies have revealed that thyroid autoimmunity and thyroid cancer may coexist, although a pathogenic relationship has not been clearly established. Graves’ disease (GD) is an autoimmune thyroid disease and is considered the most common cause of hyperthyroidism. Thyroid cancer is the most common malignancy of the endocrine system and represents the eighth most diagnosed cancer worldwide. Although in patients with GD, the presence of thyroid nodules is...

Background: Neuroendocrine tumors (NETs) represent a heterogenous group of neoplasms and their diagnosis can be challenging. In 2019, FDA approved 68Gallium labeled DOTATATE PET tracer for SSTR2 overexpressing NETs, which has been widely adopted since. However, limitations of 68Ga-DOTATATE have led to the development of additional radiotracers for the diagnosis of NETs. Herein we report on a novel PET tracer using 43Sc for DOTATATE labeling. <s...