ea0094p111 | Reproductive Endocrinology | SFEBES2023
Zamora Magdalena
, Harris David
, Davies Nils
, Ebnet Johannes
, Radermacher Peter
, Brucker Cosima
, Waller Christiane
, Pablo Robles Juan
, Bertsch Thomas
, Clapp Carmen
, Triebel Jakob
Circulating levels of the antiangiogenic protein vasoinhibin (16 kDa PRL), a fragment of prolactin, are of interest in vasoproliferative retinopathies, preeclampsia, and peripartum cardiomyopathy, but are unknown due to the lack of a quantitative assay. Here, human serum samples were investigated for the concentration and bioactivity of vasoinhibin using a novel enzyme-linked immunosorbent assay (ELISA) for human vasoinhibin employing an anti-vasoinhibin monoclonal antibody, a...