Endocrine Abstracts

Priming with sex steroids prior to stimulation tests for the diagnosis of GH deficiency (GHD) in peripubertal years remains controversial, though some evidence suggests its utility in improving the specificity of GH testing for the distinction between idiopathic GHD (IGHD) and constitutional delay of growth and puberty (CDGP). However, few data are available on the final height (FH) of untreated CDGP patients. In order to better understand the usefulness of priming, we analyze...

Hypothyroidism has been traditionally described as a frequent endocrine complication of thalassemic children: in these patients hypothyroidism is mainly of primary origin and not linked to autoimmunity (Mariotti et al., Pediatr Endocrinol Rev 2011). Fewer data are available on the prevalence and nature of this complication in adult age thalassemia. Therefore, we elected to evaluate thyroid function and autoimmunity in a large series of adult patients.<p class="abs...