Searchable abstracts of presentations at key conferences in endocrinology

ea0086en7.2 | Endocrine Consequences of Living With and Beyond Cancer | SFEBES2022

Incidence of endocrine deficits after management of brain tumours

Murray Robert

The adverse effect of childhood cancer and treatment thereof on growth was firmly established in the mid-1970’s. The impact on growth is multifactorial, however, cranial irradiation was quickly established as one of the most important contributors. Exposure of the hypothalamo-pituitary (HP) region to radiation in childhood cancer survivors is now a well-established risk factor for the development of anterior hypopituitarism. The degree of hypopituitarism can vary between ...

ea0082wa4 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2022

Non-functioning pituitary adenoma with high Ki 67 10%

Rasool Irum , Murray Robert

A 54 year old gentleman presented to the eye services with reduced vision on the right attributed to a cataract. Following cataract surgery there was no improvement and his vision declined further with reducing vision also on the left. He was reviewed in Neuro-ophthalmology clinic 29/10/21 and clinical suspicion of a pituitary lesion based on binasal retinal ganglion cell layer loss and bilateral optic atrophy prompted urgent imaging. His right eye visual acuity was to hand mo...

ea0031p130 | Clinical practice/governance and case reports | SFEBES2013

Radioactive iodine-induced hyperparathyroidism

Shankaran Vani , Murray Robert

Case history: A 27 years old lady having presented with a neck mass, underwent a total thyroidectomy for thyroid malignancy in 1967. Histology confirmed papillary carcinoma of the thyroid. In 1968, she complained of tiredness and mild neck swelling despite TSH suppressive therapy. Her thyroid uptake study showed a residuum of thyroid tissue within the neck. She went on to have radioiodine ablation therapy on two separate occasions. She responded well with no evidence of residu...

ea0025p219 | Nursing practise | SFEBES2011

Low bone mass is an infrequent long-term sequelea of pituitary disease

Lynch Julie , Murray Robert

Introduction: Within the setting of putative or established pituitary disease the primary disease process (i.e. Cushing’s disease), hormone deficits (i.e. sex steroids, GH), and inappropriate replacement therapy (i.e. glucocorticoids) are reputed to predispose to low bone mass.Patients and Methods: We examined bone mass at the lumbar spine (LS) and total hip (TH) using DXA in 259 patients with an insult to the hypothalamo–pituitary axis (51.6&#...

ea00100wb5.1 | Workshop B: Disorders of the hypothalamus and pituitary (II) | SFEEU2024

Comprehensive overview of acromegaly management

Ahmed Faroug , Murray Robert

A male patient was diagnosed with acromegaly in July 2007 (at the age of 38). His biochemistry showed IGF-1 123 (14.6-39.9) nmol/l; paradoxical rise in GH during OGTT; and evidence of hypopituitarism (Testosterone 5.2 nmol/l, LH 4.0 iu/l FSH 3.7 iu/l, SHBG 8 nmol/l and prolactin 112 mu/l) HBa1c 6.5%. MRI Pituitary revealed a poorly enhancing mass within the right side of the pituitary gland within a slightly expanded pituitary fossa. There was no parasellar extension, no compr...

ea00100oc6 | Oral Communications | SFEEU2024

Case of recurrence olfactory neuroblastoma presented with ACTH dependent Cushing syndrome

Ahmed Faroug , Murray Robert

A-49-year-old female with previous history of Olfactory neuroblastoma treated surgically in 2003 and no adjuvant treatment was given. She has a past medical history of depression, bilateral sensory neural hearing loss which is thought to be genetic. In Feb 2023 presented with uncontrol hypertension associated with hypokalaemia. Clinical examination showed BMI of 48.4, uncontrol high blood pressure despite using multiple antihypertensive medication. The initial assessment for t...

ea0031p24 | Bone | SFEBES2013

Effect of bone mineral density in patients with non-functioning pituitary adenoma

Min Aye Aye , Murray Robert

We look into total 67 patients with non-functioning pituitary adenoma and review their bone mineral density in association with age and gender, effect of radiotherapy and hormonal replacement.Age range: 5.97% (4 patients) are between 18 and 40 years, 43.28% (29 patient) between 41 and 60 years and 50.74% (34 patients) are between 61 and 86 years.Gender: 61.19% (41 patients) are male and 38.8% (26 patients) are female.<p class="...

ea0028p344 | Thyroid | SFEBES2012

Second course of anti-thyroid treatment may be suitable for some individuals with relapsed Graves’ disease.

Kyaw Tun Julie , Murray Robert

Background: Graves’ disease is widely treated with anti-thyroid medication. After an initial course of treatment, remission is achieved in around 50% of patients. Definitive treatment is generally offered in relapsed cases, based on the assumption that remission rates following a second course of anti-thyroid medication are significantly lower.Method: A database of patients with Graves’ disease has been kept from 2004. 150 patients were suitabl...

ea0028p158 | Nursing practise | SFEBES2012

Adequacy of documented evidence of education in glucocorticoid deficient patients and subsequent nurse-led initiatives

Andrew Julie , May Sophie , Murray Robert

Background: Acute adrenal insufficiency leads to potentially life threatening crises if increases in steroids are delayed or insufficient. The patient is central to early increases in dosage and informing Healthcare Professionals of their steroid-dependency.Methods: To assess adequacy of information given to cortisol deficient patients we performed an audit of case notes documentation. The audit was performed over four weeks, involving 32 patients from t...

ea00100wb3.1 | Workshop B: Disorders of the hypothalamus and pituitary (II) | SFEEU2024

A young Acromegalic patient (AIP+) with poor response to SRLs and discordant GH / IGF1

Saeed Saadia , Kyriakakis Nikolaos , Murray Robert

A 23-year-old Caucasian male was referred to Endocrinology with symptoms spanning over 7 years. He was substantially taller than other members of his family measuring 6’3”. He initially presented to Ophthalmology with preseptal cellulitis and noted to have visual field defects with acromegalic features. His pituitary profile showed GH > 100 mu/l, Total T4 104 nmol/l (normal: 60–140 nmol/l), Prolactin 234 mu/l, cortisol 240 nmol/l with flat GST. There was no ...