Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep867 | Reproductive and Developmental Endocrinology | ECE2022

Real-world evidence of follicle stimulating hormone effectiveness in male idiophatic infertility

Romeo Marilina , Spaggiari Giorgia , Nuzzo Federico , R.M. Granata Antonio , Simoni Manuela , Santi Daniele

Introduction: Male idiopathic infertility represents a therapeutic challenge for physicians, since a targeted aetiological treatment does not exist. Several hormonal and non-hormonal therapies have been proposed so far to increase pregnancy rates. Among hormonal therapies, exogenous follicle-stimulating hormone (FSH) administration shows the most convincing physiological rationale in the face of a clinical efficacy below expectations. Indeed, from evidences available in the li...

ea0081ep896 | Reproductive and Developmental Endocrinology | ECE2022

Vascular erectile dysfunction as a mirror of general health: focus on patients comorbidities

Rossi Barbara , Romeo Marilina , Granata Antonio Raffaele Michele , Rochira Vincenzo , Simoni Manuela , Spaggiari Giorgia , Santi Daniele

Background: Erectile dysfunction (ED) represents the most frequent sexual dysfunction. Among several possible ED aetiologies, vascular ED (vED) presents the greatest implications for global individual health, resulting an early hallmark of cardiovascular diseases. Indeed, vED was demonstrated associated with a 1.25 times greater risk of developing major cardiovascular diseases. Alongside cardiovascular aspect, the evaluation of patients health, measured by the comorbidities nu...

ea0093oc32 | Oral communication 5: Reproductive Endocrinology | EYES2023

Follicle stimulating hormone in male idiopathic infertility: How to predict its efficacy?

Romeo Marilina , Spaggiari Giorgia , Valentina Leonardo Dalla , Nuzzo Federico , Roli Laura , Santis Maria Cristina De , Trenti Tommaso , Granata Antonio R. M. , Simoni Manuela , Santi Daniele

Background: Testis stimulation with follicle stimulating hormone (FSH) is one of the empirical treatments proposed for male idiopathic infertility, although early reliable markers to predict its efficacy are still lacking.Objective: To identify the improvement of semen parameters required to predict a priori FSH efficacy in terms of pregnancy achievement.Methods: A real-world study was conducted, enrolling idiopathic infer...

ea0093oc34 | Oral communication 5: Reproductive Endocrinology | EYES2023

Testosterone serum levels in idiopathic male infertility: An epidemiological insight with pathophysiological and clinical consequences

Costantino Francesco , Spaggiari Giorgia , Valentina Leonardo Dalla , Romeo Marilina , Roli Laura , De Santis Maria Cristina , Trenti Tommaso , Granata Antonio , Simoni Manuela , Santi Daniele

Background: Despite male idiopathic infertility is characterized by semen analysis alteration with gonadotropins within reference ranges, it is still considered a functional hypogonadotropic hypogonadism (FHH). This simple definition is fundamental to guide the empirical therapeutic approach of these men. However, the number of studies describing total testosterone serum levels (TT) in male idiopathic infertility is still limited.Objective: To evaluate T...