ea0032p1099 | Thyroid cancer | ECE2013
Pezzani Raffaele
, Barollo Susi
, Cristiani Andrea
, Redaelli Marco
, Zambonin Laura
, Rubin Beatrice
, Bertazza Loris
, Zane Mariangela
, Mucignat-Caretta Carla
, Bulfone Alessandro
, Pennelli Gianmaria
, Rosa Pelizzo Maria
, Mantero Franco
, Moro Stefano
, Mian Caterina
Background: Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the thyroid gland, accounting for 7480% of all thyroid cancers. The T1799T>A transversion is an activating mutation of the BRAF oncogene that is common in conventional PTC and specific to it.Aims: To study the prevalence, tumorigenic role and biomolecular implications of rare BRAF variants in a large cohort of patients.Study desig...