Searchable abstracts of presentations at key conferences in endocrinology

ea0020p483 | Obesity and Metabolism | ECE2009

Aromatase expression in peripheral blood leukocytes from adult and elderly female and male subjects

Pignatti Elisa , Rossi Alessandra , Scaltriti Sara , Taliani Erica , Rochira Vincenzo , Simoni Manuela , Carani Cesare

Objective: Aromatase, the key enzyme involved in estrogen synthesis, is expressed in a variety of cells and tissues including human peripheral blood leukocytes (PBLs). The present study was designed to evaluate PBL aromatase gene expression in male and female elderly subjects compared to young male controls.Design: CYP19A1 mRNA and protein were measured in PBLs obtained from young men (n=13) aged < 35 years, postmenopausal women (n</...