Endocrine Abstracts

Long acting somatostatin analogues (SMS) are extensively used as second and even first line treatment of acromegaly. Except of the inhibition of GH secretion, somatostatin is a potent inhibitor of insulin secretion from the pancreatic b- cells. As defects of glucose homeostasis are very common in acromegaly, we decided to examine the effect of the control of GH hypersecretion with SMS on glucose metabolism.We study 44 acromegalic patients divided in 3 gr...