ea0031p183 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013
Mkhwanazi Blessing
, Sibiya Ntethelelo
, Serumala Metse
, Myburg Rene
, Musabayane Cephas T
The onset of diabetic complications is attributed to sustained hyperglycemia which triggers the generation of free radicals and oxidative-related damage in the retina, renal glomerulus and peripheral nerves. Recent studies report that intense glycaemic control by the subcutaneous administration of insulin cannot completely restore the balance between reactive oxygen species and antioxidants. Preliminary studies in our laboratory indicate that transdermally delivered Syzygi...