Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep848 | Late Breaking | ECE2021

EGFR (Epidermal Growth Factor Receptor) expression in tumor microenvironment of pituitary adenomas – pathogenic and therapeutic implications

Silvia Corlan Ana , Anca Maria Cimpean , Marius Raica

BackgroundPituitary adenomas are general benign tumors. However, gross invasion at time of operation is observed in up to 35% of pituitary adenomas. The new WHO classification describes pituitary tumor subtypes along with histological markers, such as Ki67 > 3%, that may suggest a potential for aggressive clinical behavior. The expression of EGFR in tumor microenvironment of pituitary adenomas ant its correlation with tumor behavior have been poorly ...

ea0073aep889 | Late Breaking | ECE2021

Emergency total thyroidectomy in a COVID 19 patient with Graves’ disease and pancreatitis induced by methimazole

Balas Melania , Varcus Flore , Daniela-Georgiana Amzar , Golu Ioana , Plotuna Iulia , Borlea Andreea , Silvia Corlan Ana , Vlad Mihaela

IntroductionThe use of antithyroid drugs is associated rarely with severe hepatotoxicity. Recently, due to several cases reported in the literature, acute pancreatitis was added as a severe potential adverse effect induced by methimazole. The physiopathology of methimazole induced pancreatitis is not fully understood (intrinsic toxicity or idiosyncratic drug reaction were proposed as possible mechanisms). If adverse effects occur and no other treatment o...