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ea0081oc5.2 | Oral Communications 5: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2022

Once-weekly semaglutide delays a late phase gastric emptying of solid meal measured by repeated scintigraphic imaging in obese women with PCOS

Jensterle Mojca , Ferjan Simona , Lezaic Luka , Socan Aljaz , Zaletel Katja , Janez Andrej

Background: GLP-1 agonism have the potential to affect gastric emptying (GE), yet the reports for subcutaneous semaglutide, currently the most effective GLP-1 RA approved for weight management, remain inconclusive. It has been demonstrated that semaglutide either had no effect on GE or it delayed GE only within the first hour, without late phase retention. Notably, those conclusions were made by an indirect method of estimation of GE through ingestion, absorption and determina...

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Endocrine Abstracts

Once-weekly semaglutide delays a late phase gastric emptying of solid meal measured by repeated scintigraphic imaging in obese women with PCOS

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