Searchable abstracts of presentations at key conferences in endocrinology

ea0026p610 | Clinical case reports | ECE2011

Cholestatic jaundice methimazole-induced or secondary to heart failure?

Souto S B , Rodrigues P , Belo S , Nogueira C , Magalhaes A , Castedo J L , Carvalho-Braga D , Carvalho D

Methimazole-induced cholestatic jaundice is a rare adverse effect, dose-dependent, occurring within the first 3 months of use, usually reversible within 3 months after discontinuing drug therapy.Case report: Woman, 64 years, history of hyperthiroidism since August 2009, under therapy with methimazole 5 mg/day. The patient was referred to endocrinology department in March 2010, with history of heart failure, atrial fibrillation, type 2 diabetes mellitus, ...

ea0026p699 | Diabetes complications | ECE2011

Gilbert syndrome and diabetes: a perfect union?

Matos M J , Souto S B , Oliveira A I , Silva S , Vinha E , Freitas P , Queiros J , Braga D C , Carvalho D

Introduction: Gilbert syndrome is one of the most common inherited diseases, with a prevalence of 5–7%. It is caused by a mutation in UGT1A1 gene, which is in turn responsible for a deficiency in bilirubin glucuronidation. It courses with unconjugated hyperbilirubinemia, and jaundice may occur in adolescence, after fasting, exercise, or in menses, and also with certain drugs. Individuals with Gilbert syndrome seem to have a reduction in the prevalence of micro- and macrov...