ea0035p948 | Steroid metabolism and action | ECE2014
Ibanichuka Jacqueline
, Vincent Royce P
, Ghataore Lea
, Taylor Norman F
, Millward Ann
, Pinkney Jonathan H
, Stenhouse Elizabeth
Background: Polycystic ovarian syndrome (PCOS) affects 510% of women of reproductive age. Hyperandrogenism and hyperinsulinaemia have been attributed to the pathophysiology of PCOS. The aim of this study is to evaluate the effect of fat distribution and insulin resistance on steroid metabolism in PCOS.Methods: The study recruited 20 PCOS and 20 matched controls. Fat distribution was assessed by waist circumference, skin fold measurements, and body ...