Endocrine Abstracts

A 54 years old gentleman was admitted to cardiology ward from echocardiography department in view of findings on the scan. He was referred to cardiology clinic on outpatient basis 3 months earlier by his GP for his shortness of breath, ankle swelling and a murmur heard on auscultation by his GP. His transthoracic echocardiography was being conducted prior to attendance at cardiology clinic. The result showed a large global pericardial effusion, max 4.9 cm in size. There was se...

A 24 years old veterinary nurse presented to the cardiology outpatient clinic with palpitations, breathlessness and lethargy. There was no history of weight loss. She had a past history of bulimia. She was clinically euthyroid. ECG demonstrated sinus tachycardia with heart rate of 120 bpm. Thyroid functions test (TFT) done by GP was normal. She was initially treated with beta-blockers.She was subsequently admitted to hospital a month later with palpitati...

A 36 year-old female presented with increasing headaches over the previous 8 months. She had seen in the neurology clinic recently and treated for migraines and cluster headache. She also had a history of depression. She had prodromal aura of visual disturbance including blurred vision and photophobia.She was admitted following sudden onset of stabbing pain over the left eye along with nausea. All these symptoms were classic of her usual migraines. On ad...

Background: Metastatic insulinomas are very rare (fewer than 1:100000) and therefore may pose a therapeutic challenge as there are no case controlled studies comparing the efficacy of various therapeutic approaches avialable. The Ki 67 index from the histology of the primary tumour is an established prognostic marker for metastatic disease with tumours showing low Ki 67(<3%) being defined as low risk of early recurrence.Case Presentation: A 60 year o...

Background: The published data on the natural history of (presumed) non-functioning pituitary microadenomas (micro-NFAs) is possibly compromised by small sample sizes, short follow-up and inclusion of cases with other pathologies in the analyses.Objective: To clarify the long-term outcomes of micro-NFAs in a large cohort of patients.Methods: We conducted a multi-centre, retrospective, cohort study involving 22 UK endocrine departme...