ea0019p133 | Diabetes, Metabolism and Cardiovascular | SFEBES2009
McNeilly A
, Williamson R
, Balfour D
, Sutherland C
, Stewart C
The incidence of type 2 diabetes (T2DM) has doubled over the past decade. Obesity induced insulin resistance is associated with T2DM and the metabolic syndrome (including hypertension, and dyslipidemia). Diets high in saturated fat are largely to blame for the current obesity epidemic. High-fat feeding of animals increases circulating corticosterone levels, in addition to changes in glucose homeostasis. The relationship between insulin sensitivity and abnormal hypothalamic...