Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep372 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

The effect of SNP (rs174537) in FADS1 gene on fatty acid composition in serum lipids

Metelcová Tereza , Vaňková Markéta , Zamrazilová Hana , Hovhannisyan Milena , Tvrzická Eva , Staňková Barbora , Hill Martin , Včelák Josef , Kunešová Marie

Background: Fatty acid desaturase 1 (FADS1) gene controls the fatty acid metabolism pathway in the human body (Sergeant et al., 2012). Single nucleotide polymorphism (SNP) in FADS1 gene and percentage of polyunsaturated fatty acids inserum lipids was associated (Klingel et al., 2018). Genetically predisposition to higher plasma arachidonic and stearic acid levels were associated with incidence oflarge-artery stroke and venous thromboembolism...