ea0021p19 | Bone | SFEBES2009
Loh Nellie Y
, Stechman Michael J
, Schulz Herbert
, Jeyabalan Jeshmi
, Reed Anita A C
, Ahmad Bushra
, Stewart Michelle
, Brown Steve D M
, Huebner Norbert
, V. Thakker Rajesh
Renal stone disease is a common disorder for which the underlying causes remain largely unknown. We have investigated a hereditary renal calcification mouse model, Rcalc1, that is not associated with hypercalciuria for underlying mechanisms. Kidney RNA from 30 to 33 week-old Rcalc1 and control BALB/c and C3H female mice (n=4/group) was extracted and hybridised to Mouse Genome 430 2.0 arrays (Affymetrix). Following Robust Multichip Average normalization, pair-wise compar...