Searchable abstracts of presentations at key conferences in endocrinology

ea0099p276 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Cell cycle synchronization enhances insulin secretion in MIN6 cells

Pramanik Tapabrata , Verma Prachi , Mittal Aditya

Type I diabetes mellitus (DM) is characterized by an autoimmune destruction of the pancreatic β-cells that leads to absolute insulin deficiency. However, T1DM individuals undergoing exogenous insulin therapy may show partial remission of endogenous insulin secretion and better insulin sensitivity, and this remission may range between few months to many years. This partial remission is known as the ‘honeymoon phase,’ and extending the duration of this remission h...