Searchable abstracts of presentations at key conferences in endocrinology

ea0082wd11 | Workshop D: Disorders of the adrenal gland | SFEEU2022

Gabapentin induced low cortisol

Wahid Alam , Srinivasan Ramalingam

A 56 year old man with history of Hypertension, “Pre-diabetes” and Osteoarthritis was noted to have a low morning Cortisol of 31 nmol/l at 0912 hrs and <28 nmol/l at 0741 hrs on the first and 4th postoperative days respectively following a left total knee replacement. His regular medications were Amlodipine 5mg OD, Ramipril 5mg OD, Bisoprolol 3.75mg OD, Atorvastatin 20mg HS, Gabapentin 100mg TDS. Post operatively he was also given Zomorph 10mg BD with Oramorph PR...

ea0086p321 | Bone and Calcium | SFEBES2022

Unusual Association of Hypercalcemia in a Patient with Coeliac Disease

Ramalingam Satheekshan , Wahid Alam , Srinivasan Ramalingam

A female born in 1950, with history of Coeliac Disease since 1985, hypolactasia, pernicious anaemia, osteoporosis, asthma, lymphocytic colitis and non-alcoholic fatty liver disease with portal hypertension was referred to the Endocrinology team in June 2021 as the calcium was noted to be high. She had strongly positive anti endomyseal antibody, high Tissue Transglutaminase tire and duodenal biopsy proved villous atrophy with no evidence of Enteropathy associated T cell Lymphom...

ea0094p191 | Bone and Calcium | SFEBES2023

Spontaneous remission of hypercalcaemia in PHPT due to necrosis of parathyroid adenoma

Wahid Alam , Turner Jeremy , Pain Simon

Primary hyperparathyroidism (PHPT) affects approximately 0.3% of the UK population. The most frequent cause is solitary parathyroid adenoma, less commonly parathyroid hyperplasia, multiple adenomas, and parathyroid carcinoma. Cinacalcet is a calcimimetic which may be used in treatment of PHPT in certain circumstances. We report here a case of PHPT, treated by Cinacalcet, wherein apparently spontaneous necrosis of a parathyroid adenoma and resolution of hypercalcaemia occurred....

ea0086p320 | Bone and Calcium | SFEBES2022

Primary Hyperparathyroidism in a patient with Alport syndrome

Wahid Alam , Ramalingam Satheekshan , Ross Callum , Srinivasan Ramalingam

A 50 years old man was seen in the Endocrine clinic with elevated calcium (2.80 mmol/l, normal 2.20-2.60) and Parathyroid hormone (10.7 pmol/l, normal 1.6-6.9) levels. His medical background includes Alport Syndrome, Renal Allografts (1st 1990, 2nd 2000 and 3rd 03/11/2005), and Osteopenia on DEXA scan in February 2020. He did not have any renal stones in the past. There was no family history of hypercalcemia. He was on Vitamin D 1000 Units daily (Vitamin D 55 nmol/l, normal 50...

ea0082we2 | Workshop E: Disorders of the gonads | SFEEU2022

47, XYY syndrome: hypogonadism and osteoporosis

Srinivasan Ramalingam , Ramalingam Satheekshan , Wahid Alam , TunYee LainLai , Thomas Joegi , Makkuni Damodar

A male, born in 1957, with history of familial spinocerebellar ataxia, Type 2 diabetes (diagnosed in 1999), asthma, learning difficulties, chronic pancreatitis, recurrent falls, multiple low trauma fractures and osteoporosis was referred to Endocrinology Department in 2019. He sustained a right radial fracture at the age of 34 (1992), followed by comminuted right distal radius and Ulna styloid process fracture in 2002, Left and right Neck of Femur fractures in 2013 and 2014 re...