ea0077p171 | Metabolism, Obesity and Diabetes | SFEBES2021
Thomas Benjamin
, Suckacki Karla
, Fyfe Claire
, Tavares Adriana
, Sulston Richard
, Lovdel Andrea
, Woodward Holly
, Han Xuan
, Mattiucci Domenico
, Brain Eleanor
, Alcaide-Corral Carlos
, Gray Gillian
, Whitfield Phillip
, Stimson Roland
, Morton Nicholas
, Johnstone Alexandra
, Cawthorn William
Caloric restriction (CR) is a nutritional intervention that reduces the risk of age-related diseases in numerous species, including humans. CRs metabolic effects, including decreased fat mass and improved insulin sensitivity, play an important role in its broader health benefits, yet many aspects of the CR response remain poorly understood. In particular, sex differences in metabolic function are increasingly well recognised, but the extent and basis of sex differences i...