Searchable abstracts of presentations at key conferences in endocrinology

ea0020p59 | Thyroid | ECE2009

Real-time elastography and contrast-enhanced ultrasound for the assessment of thyroid nodules

Friedrich-Rust Mireen , Sperber Andrea , Holzer Katharina , Gruenwald Frank , Badenhoop Klaus , Bechstein Wolf , Zeuzem Stefan , Bojunga Joerg

Background and aims: The aim of the present study was to evaluate real-time elastography (RTE) and contrast-enhanced ultrasound with Sonovue (CEUS) for the differentiation of benign and malignant thyroid nodules using cytologic/histologic analysis as reference method. While first studies have reported excellent results of RTE for the differentiation of thyroid nodules, data on CEUS of the thyroid are rare.Methods: RTE was classified as: score 1=soft, 2=p...

ea0022p381 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

CYP24A1 haplotypes are associated with differentiated thyroid carcinoma

Penna-Martinez Marissa , Ramos-Lopez Elizabeth , Stern Julienne , Kahles Heinrich , Hinsch Nora , Hansmann Martin-Leo , Selkinski Ivan , Grunwald Frank , Vorlander Christian , Wahl Robert A , Bechstein Wolf O , Zeuzem Stefan , Holzer Katharina , Badenhoop Klaus

Background: Previously, we reported an association of vitamin D receptor (VDR) polymorphisms and differentiated thyroid cancer (DTC) risk. The aim of the present study was to investigate other vitamin D pathway genes such as CYP27B1, CYP2R1 and CYP24A1 which code for enzymes that, respectively, synthesize and degrade 1,25(OH)2D3 in patients with DTC and healthy controls (HC). Also its influence on 25(OH)D3 and 1,25(OH)2D3 ...