Searchable abstracts of presentations at key conferences in endocrinology

ea0095oc9.6 | Oral Communications 9 | BSPED2023

How does HbA1c compare with OGTT in identifying patients with Diabetes Mellitus and Pre-Diabetes

Sims Jack , Worth Chris , Manfredonia Claire , Ginbey Eleanor , Skae Mars

Introduction: The incidence of Type 2 Diabetes Mellitus (T2DM) is rapidly increasing within the paediatric community, prompting searches for a simple and effective screening tool. Oral glucose tolerance test (OGTT) is the gold standard but is poorly accessible in the community. HbA1c offers an alternative which can be easily performed, but cut-offs for children have been extrapolated directly from the adult American Diabetes Association (ADA) diagnostic criter...

ea0078p44 | Miscellaneous | BSPED2021

Interpretation of CGM-measured nocturnal hypoglycaemia in congenital hyperinsulinism

Yang Leyi , Worth Chris , Salomon Estebanez Maria , O‘Shea Elaine , Banerjee Indi

Background: Congenital Hyperinsulinism (CHI) is characterised by dysregulated and excess secretion of insulin leading to severe hypoglycaemia. Monitoring of glucose levels is essential in this condition as prolonged hypoglycaemia can cause life-threatening complications such as permanent neurological impairment. Interstitial glucose monitoring by continuous glucose monitoring (CGM) devices can identify nocturnal hypoglycaemia retrospectively through data analysis. Analysis can...

ea0095p132 | Miscellaneous/other 2 | BSPED2023

Initial accuracy and family experience evaluation of the Dexcom G7 continuous glucose monitor for hypoglycaemia due to hyperinsulinism

Worth Chris , Worthington Sarah , Ahmad Sumera , O'Shea Elaine , Salomon-Estebanez Maria , Banerjee Indraneel

Background: For children with congenital hyperinsulinism (HI), detection and avoidance of hypoglycaemia is the cornerstone of clinical management and poses significant demands on families. Standard of care remains intermittent fingerprick monitoring but the lack of predictive information has resulted in continuous glucose monitoring (CGM) increasing in popularity. Accuracy is suboptimal in this group and family feedback identifies various barriers to use. We a...

ea0085oc5.9 | Oral Communications 5 | BSPED2022

Evaluation of a low postnatal hypoglycaemia threshold

Worth Chris , Ramya Gokul Pon , R Hashim , H Porte , Worthington Sarah , Dunne Mark , Estebanez Maria Salomon , A Mahaveer , Banerjee Indi

Background and objective: Neonatal hypoglycemia is common and frequently self-resolving, although rare due to congenital hyperinsulinism are associated with high risk of brain injury. The time period for neonatal hypoglycemia has been described in several studies. It is unknown if low hypoglycemia thresholds (<2.0 mmol/l) lead to missed cases of persistent hypoglycaemia. We aimed to ascertain if lower hypoglycemia threshold risked missing persistent forms of hypoglycemia i...