Endocrine Abstracts

Graves’ disease (GD) is a common cause of hyperthyroidism. Associated hematological complications rarely occur. Most review articles describe it as a rare manifestation and often reported as isolated cases or series. These disorders in hyperthyroidism may stem from the primary thyroid pathology or its treatment. In untreated primary hyperthyroidism, effects on hematological parameters range from mild single lineage involvement to pancytopenia. The most feared treatment re...

Hemoglobin A1c (HbA1c) is formed from the addition of a glucose residue to the N terminus of the Beta chain of a hemoglobin molecule via a non-enzymatic glycation pathway. Its levels correlate with the ambient plasma glucose concentration. The 120-day life span of red blood cells makes HbA1c a useful tool to approximate the diabetic control of patients over three to four months. It has also been found to be an accurate predictor of the microvascular and macrovascular complicat...