Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep427 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

The role of deferoxamine (DFO) in insulin resistance and diabetes

Ahn So-Yeon , Woo Song Min , Yeop Jeong Jae , Ho Kim Tae , Choi Sung-E , Kang Yup , Jin Kim Hae , Young Jeon Ja , JIN Han Seung , Lee Nami , Lee Kwan-Woo

Iron also plays an important role in many physiological processes, including redox balance, inflammation, and metabolism. It is reported perturbation of iron (Fe) homeostasis has also been associated with metabolic diseases. Iron reduction, with iron chelator, has preventive effects in cardiovascular remodeling and obesity. On the other hand, deferoxamine (DFO) increases hypoxia and collagen production in the kidney. Thus, the effects of DFO on metabolic disease remains contro...