Endocrine Abstracts

Introduction: Calcitonin (CT) is the most specific marker for medullary thyroid carcinoma (MTC), thus, even low detectable values can conceal persistent disease. Current guidelines suggest performing an early CT evaluation three months after surgery. However, this timing may be too premature to evaluate the CT nadir, since different isoforms or aggregates from tumour deposits may persist in the bloodstream and require additional time to be cleared. The present study aimed to e...

Introduction: Indeterminate cytology still puzzles clinicians, due to its wide range of oncological risks. The new Italian cytological classification introduced in 2014 by SIAPEC-IAP split this category into TIR3A and TIR3B, according to a different cancer risk of <10% and <30%, respectively. Consequently, TIR3B nodules still have a surgical indication, even if more than half of cases will not result in thyroid cancer. The present study aims to analyse a consecutive se...