Endocrine Abstracts

A 75 year old male presented in August 2017 with dizziness, nausea and weight loss. In ENT clinic he was found to have right vocal cord lesion. He had CT chest, abdomen and pelvis which showed mediastinal and hilar lymphadenopathy and bilateral adrenal lesions. A PET–CT scan showed intense metabolic uptake in the adrenals with low volume, but moderately active mediastinum and hilar lymphadenopathy. He was presumed to have adrenal and mediastinal Tuberculosis and was start...

A 64 years old female presented with frontal headache and sinusitis like features. Later she got double vision when she woke up in the morning. No eye pain or vision loss. No weakness in the limbs. No neck pain. On examination: BP, heart rate and other observations within normal limits. No postural hypotension. Diplopia on left lateral gaze, very limited abduction of left eye. Other cranial nerves intact. Normal visual fields. No signs of Cushing’s. No motor or sensory de...

A 43 year old female experienced sudden sever back pain after lifting her baby’s buggy in January 2014. In October 2013, she had an emergency caesarean section to deliver her baby. This was performed for a prolonged first stage of labour with foetal distress. She breast fed her baby for 16 weeks. Her baby was conceived in early 2013 on the first attempt using donor egg and sperm. Her husband was found to have azoospermia. They therefore approached a Fertility Clinic and s...

A 28-year-old woman presents with a one-year history of marked weight gain of 18 kg, increasing hirsutism and night sweats. Clinically, hyperandrogenism and Cushing’s syndrome were suspected. A diagnosis of Polycystic ovarian syndrome was made based on Rotterdam criteria and Metformin was initiated. Initial testing for Cushing’s syndrome demonstrated a high 24 h urinary free cortisol (306 nmol/l) with incomplete cortisol suppression on an overnight dexamethaso...