ea0099oc1.4 | Oral Communications 1: Reproductive and Developmental Endocrinology | ECE2024
Patel Bijal
, Abbara Ali
, Yeung Arthur
, Phylactou Maria
, Tsoutsouki Jovanna
, Koysombat Kanyada
, Young Megan
, Nyunt Sandhi
, Qayum Ambreen
, Patel Aaran
, Zielinska Agata
, Omar Yusra
, Eng Pei
, Mills Edouard G
, Hanassab Simon
, Webber Lisa
, Jayasena Channa
, Tan Tricia
, Quinton Richard
, Clarke Sophie
, Comninos Alexander
, Dhillo Waljit
Background: Polycystic Ovary Syndrome (PCOS) and Functional Hypothalamic Amenorrhoea (FHA) are the two commonest causes of menstrual disturbance in pre-menopausal women. In practice, differentiating these two common reproductive disorders can be challenging. A fundamental abnormality that underpins both conditions is altered gonadotrophin releasing hormone (GnRH) pulsatility, being increased in PCOS but reduced in FHA. Likewise, congenital (e.g. congenital hypogonadotropic hyp...