Searchable abstracts of presentations at key conferences in endocrinology

ea0063p637 | Interdisciplinary Endocrinology 1 | ECE2019

Polyphenol health effects on cardiovascular and neurodegenerative disorders: a meta-analysis

Spaggiari Giorgia , Poti Francesco , Zimetti Francesca , Zanotti Ilaria , Santi Daniele

Background: Polyphenols are proposed as protective factors against the occurrence of degenerative diseases affecting several systems, such as cardiovascular and neurocognitive ones. The beneficial effect of polyphenol-enriched diets is assumed to be multifactorial, including direct antioxidant and anti-inflammatory properties, as well as the polyphenol-related capability to modulate lipid metabolism and gut microbiota function. However, the prediction of polyphenolsÂ’ impa...

ea0063gp69 | Reproductive Axis | ECE2019

Male patients with hypogonadism have an impaired lipoprotein function

Cangiano Biagio , Adorni Maria Pia , Zimetti Francesca , Vezzoli Valeria , Bernini Franco , Caruso Donatella , Corsini Alberto , Sirtori Cesare R. , Cariboni Anna , Ruscica Massimiliano , Bonomi Marco

Background: Male hypogonadism is known to be associated with an increased incidence of cardiovascular (CV) events, although the underlying biochemical mechanisms are so far not fully understood. The clinical condition characterized by low levels of testosterone offers a unique model to unravel the possible role of lipoprotein-associated abnormalities in CV risk. In particular, the assessment of the functional capacities of high-density lipoproteins (HDL) may provide novel insi...