Endocrine Abstracts

Background: Simultaneous bilateral petrosal sinus sampling is valuable in differentiating the etiology of ACTH dependent Cushing’s syndrome. It is used to locate the source of ACTH production when pituitary magnetic resonance imaging is negative.Nurses’ role: Specially trained endocrine nurses are part of the team for inferior petrosal sinus sampling. They prepare necessary material and documentation, mark all test tubes, handle the samples tak...

Normal linear growth in children is highly complex process, regulated by interaction of genetic, environmental and hormonal factors.We present four growth hormone deficient patients which despite severe growth hormone deficiency according to the provocative tests (ITT or GHRH+GHRP-6) and decreased IGF I level grew normally. This study was approved by Ethical Committee of University Clinical Center Belgrade. Three of our patients had idiopathic multiple p...

Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease caused by Hantavirus. One of the rare complications of this disease is hypopituitarism (only sporadically reported) due to hemorrhage, necrosis and atrophy of anterior pituitary lobe. The aim of the study was to investigate the anterior pituitary function in patients who recovered from HFRS.We evaluated 31 patients (29 male and 2 female), aged 38.7±2.2 years, with BMI 25.7±0...

Inhibin B is a product of the gonads and it is a marker for ovarian follicular development. We studied leptin, inhibin B and LH levels in two groups of patients with AN, at low weight (n=20, BMI=14.3 plus/minus 0.3 kg/m2) and after they reached goal weight and restore menstrual cycles (n=13, BMI 19.3 plus/minus 1.0 kg/m2). Nineteen eumenorrheic females (BMI 19.8 plus/minus 0.4 kg/m2) served as controls. At low weight in patients with AN, basal leptin (1.1 plus/minus 0.2 ng/L),...

Anorexia nervosa (AN) is a product of complex interactions between physiological and psychological processes. Nausea, gastric pain and fullness are common features of AN patients. The aim of the study was to investigate the effects of therapy and psychological conditions on body weight restoration in patients with AN. In 21 AN patients (age 22.4±0.7 yrs) with gastric problems at low weight (BMI 15.9±2.3 kg/m2). oesophagogastroduodenoscopy with gastric biop...