Searchable abstracts of presentations at key conferences in endocrinology

ea0051oc7.1 | Oral Communications 7 | BSPED2017

JUMP: Maternal family history of diabetes and non-white ethnicity adversely affects beta cell response in young people with Type 2 Diabetes

Dias Renuka , Aston Kayleigh , tornese gianluca , Dunger David , Wales Jerry , Hamilton-Shield Julian , Barnett Anthony , Barrett Timothy

Background: Type 2 diabetes (T2D) in children and adults continues to rise. The relative contribution of pancreatic beta cell failure is not established. We aimed to analyse beta cell function in a subgroup of the UK T2D (JUMP) cohort.Methods: Participants were recruited at 58 hospital centres across England and Wales (n=204). Patients were 5–18 years, diagnosed with T2D (ADA criteria) and a BMI SDS>+1.0. At baseline, demographics, clin...

ea0070aep778 | Reproductive and Developmental Endocrinology | ECE2020

Case-control study on ACE2 expression in children with short stature

Tornese Gianluca , Tonon Federica , Nicolardi Francesca , Toffoli Barbara , Chiara Pellegrin Maria , Barbi Egidio , Fabris Bruno , Bernardi Stella

Background: Short stature is one of the most common presentations to paediatric endocrinologists. It is estimated that despite all the exams, in 50–90% of cases, children are labelled as having idiopathic short stature. It has been recently reported that genetic ACE2 deficiency is associated with reduced body weight as well as with impaired gestational weight gain and fetal growth restriction in pregnancy. It has been argued that ACE2 deficiency, which is usually associa...