Searchable abstracts of presentations at key conferences in endocrinology

ea0025pl6biog | Society for Endocrinology Medal Lecture | SFEBES2011

Society for Endocrinology Medal Lecture

Williams G R

G R Williams, Imperial College London, London, UK. AbstractGraham R Williams obtained a BSc in Anatomy and MBBS from St Thomas’s Hospital, London and undertook PhD studies in Molecular Endocrinology at Birmingham University. He trained as a Howard Hughes and MRC Fellow at Harvard Medical School, USA and was an MRC Clinician Scientist Fellow in Birmingham. He was appointed Senior Lecturer at the Royal Postgraduate...

ea0022p288 | Diabetes | ECE2010

Comparative and metabolic study of glycosylated hemoglobin, magnesium, nitrogenous metabolites, and lipid profile in diabetics and non-diabetics patients

Mehrotra Vinit , Awasthi G

Diabetes is the major health care problem in developing countries like India. According to WHO survey total number of diabetics patients in India alone is 3.2 cores with fastest growing population of diabetics. This is not a single disease, rather a group of disorders associated with rearrangement in carbohydrate, protein and fat metabolism.Diabetes is characterized by the elevation of blood glucose level resulting from defects in insulin secretion or ac...

ea0019s9biog | Clinical Endocrinology Trust Lecture | SFEBES2009

Clinical Endocrinology Trust Lecture

Johnston Desmond G

Desmond G Johnston, Campus Dean, St Mary’s Hospital Campus, Imperial College London, London, UK Director, UK Diabetes Research Network AbstractProfessor Johnston trained in Edinburgh and Southampton where, as an MRC Training Fellow, he did his PhD with Professor George Alberti. His work at that time investigated metabolic disturbances in liver disease and metabolic aspects of endocrinology.I...

ea0019s39 | Novel aspects of bone physiology in relation to osteoporosis treatment | SFEBES2009

AMEND Young Investigators Award

Williams G R

Osteoporosis is characterised by bone fragility with increased susceptibility to fracture. The burden of osteoporosis already costs the NHS over £1.7 billion per annum but its prevalence is increasing. The skeleton is continually remodelled in response to endocrine, paracrine and mechanical signals by the coupled activities of osteoclasts and osteoblasts. Nevertheless, the continuous process of bone turnover results in an inexorable loss of bone because osteoblast-mediate...

ea0015s2biog | Society for Endocrinology Transatlantic Medal Lecture | SFEBES2008

Society for Endocrinology Transatlantic Medal Lecture

Rosenfeld Ron G

Ron G Rosenfeld, Lucile Packard Foundation for Children's Health, Stanford University, Palo Alto, CA., USA. AbstractRon G Rosenfeld, MD, is the Senior Vice-President for Medical Affairs at the Lucile Packard Foundation for Children's Health at Stanford University. He is Professor of Pediatrics at Stanford University, as well as Professor and Chair (emeritus) of Pediatrics and of Cell and Developmental Biology at Oregon...

ea0013s60 | Thyroid cancer – more than a lump in the neck | SFEBES2007

Helping the patient through different types of thyroid cancer

Dyer Robert G

Patients with thyroid cancer usually present with a lump in the neck. However, the vast majority of patients with lumps in the neck do not have thyroid cancer. The practical investigation and management of patients with lumps in the neck will be discussed, with reference to national and international guidelines. Diagnostic dilemmas and controversies will be highlighted.The types of thyroid cancer will be reviewed, with reference to their clinical behavio...

ea0011p889 | Thyroid | ECE2006

Application of MRI in the differential diagnosis of different forms of Hashimoto’s thyroiditis in patients from the iodine deficient region

Vagapova G , Mikhailov I

The purpose of this study was to describe MRI signs of Hashimoto’s thyroiditis (HT) in patients from the iodine deficient region.30 euthyroid patients with HT from the iodine deficient region and 5 healthy individuals were examined by MRI in FSE T1 and T2 pulse sequences. The diagnosis was confirmed according to the standard criteria.The atrophic form of HT (2 cases) showed the reduction of thyroid volume with denominated lobu...

ea0010p15 | Clinical case reports/Governance | SFE2005

Is Graves’ disease severity influenced by genes: a tale of two identical twins

Iqbal N , Thomson G

We report the cases of two identical twins with Graves’ disease which proved very difficult to control and followed very similar stormy course. Twin A was a 20 years old female of 12 weeks gestation when she was referred to endocrine clinic with history of weight loss, palpitations and tremor. Her thyroid function tests revealed TSH <0.08 mU/L (0.03–4.30), FT4 82.5 pmol/L (12–22 pmol/L) and FT3 44.4 pmol/L (2.8–7.1) with positive thyroid receptor ant...

ea0010p16 | Clinical case reports/Governance | SFE2005

Hyperemesis gravidarum causing malnutrition related glucose intolerance: a clinical vignette

Thomson G , Iqbal N

We report the case of a 27 year old female who was referred to our diabetes team from the antenatal clinic, when she was found to have an abnormal glucose tolerance at 16 weeks of gestation (fasting and 2 hours blood glucose values of 5.1 mmol/L and 12.2 mmol/L respectively). At the same time she was suffering with severe hyperemesis gravidarum for many weeks and had suffered significant weight loss (thyroid function tests were unremarkable). She had no specific symptoms to su...

ea0010p17 | Clinical case reports/Governance | SFE2005

The challenge of managing unresponsive thyrotoxicosis in pregnancy

Iqbal N , Thomson G

We report the case of a 22-year old woman with aggressive Graves disease. She was initially found to be clinically and biochemically thyrotoxic in June-2001 when she presented with severe thyroid eye disease. Treatment was commenced with carbimazole but she failed to adequately comply with therapy and follow-up appointments. She fell pregnant whilst thyrotoxic and was converted to propylthiouracil (dose gradually increased due to poor response). She then left the area and had ...