Searchable abstracts of presentations at key conferences in endocrinology

ea0059ep93 | Reproduction | SFEBES2018

The challenge of diagnosing 5-alpha-reductase deficiency post gonadectomy

Miles Stephanie , Shears Deborah , Shine Brian , Grossman Ashley , Pal Aparna

A 35 year old woman was referred to Endocrinology after imaging investigating unexplained pyrexia demonstrated an absent uterus. She was of Pakistani origin and was born phenotypically female with reported normal female genitalia. During late teenage years she experienced virilisation with deepening voice, increased pubic and axillary hair and clitoromegaly. She had absent breast development. Her parents were first cousins and siblings were unaffected. Investigations in Pakist...

ea0070aep79 | Adrenal and Cardiovascular Endocrinology | ECE2020

Endothelial vascular adrenal cyst with unusual presentation

Lichewitz Gavriel , Pal Marina , Karine Atlan , Mazeh Haggi

Primary adrenal cysts are a relatively rare form of lesions with incidence of 0.06% in general population and higher prevalence in women (female-to-male ratio 2.3:1). Adrenal endothelial cysts are the most common form of adrenal cysts subtypes (45%) and they usually present with abdominal or flank pain, or nonspecific symptoms . Adrenocortical carcinomas are a rare condition as well, with an incidence of 1–2 per million per year. The typical clinical presentation may inc...

ea0025p79 | Clinical biochemistry | SFEBES2011

A case of lymphocytic hypophysitis

Krishnan Simmi , Davis Julian , Pal Piyali , Gnanalingham Kanna , Wu Fredrick

A 22-year-old pregnant lady presented to the Emergency Department (ED) at 36 weeks of gestation with sudden onset of severe headache and blurring of vision. On examination, she was alert, conscious (GCS: 15/15) and had bitemporal hemianopia, confirmed on formal visual field assessment. MRI brain scan (limited views due to pregnancy) showed a pituitary mass extending into the suprasellar region and reaching the optic chiasm. Serum prolactin (PRL) was elevated at 3876 μ/l (...

ea0022p250 | Clinical case reports and clinical practice | ECE2010

Different manifestations of polyglandular autoimmune syndrome in HLA-identical monozygous twins

Csajbok Eva , Magony Sandor , Valkusz Zsuzsanna , Panczel Pal , Julesz Janos

The polyglandular autoimmune syndromes (PAS) comprise a wide spectrum of autoimmune disorders and are divided into a very rare juvenile (type I) and a relatively common adult type with (type II) or without adrenal failure (PAS III). For PAS II/III, susceptibility genes are known inreasing the risk for developing autoimmune disorders, but without being causative. Actual diagnosis of PAS involves serological measurement of organ-specific autoantibodies and subsequent functional ...

ea0021p260 | Pituitary | SFEBES2009

Solitary pituitary metastasis from carcinoma of the prostate: a case report

Farook Seleena , Gnanalingham Kanna , Pal Pyali , Kearney Tara

Mr GC aged 67 presented to the ophthalmologists in December 2008 with blurring vision and headaches. Visual acuity was 6/9, 6/24 and reassured. Two weeks later he returned as an emergency with severe visual loss of left eye to finger movements and temporal field defect right eye.Past history included cancer prostate, gleason score-7 (T2 N0). TURP performed in January 08 followed by hormonal therapy and external beam irradiation.Neu...

ea0013p76 | Clinical practice/governance and case reports | SFEBES2007

Acute falciparum malaria and parathyroid function

Pal Aparna , Karavitaki Niki , Wass John , Simpson Hugh

We present a rare case of acute falciparum malaria complicated by hypocalcaemia while having normal renal function.Case: A 64 year old African lady presented with a 2 week history of lethargy, weakness and oliguria. She had returned from Malawi a fortnight previously and had not taken antimalarial prophylaxis. Her malaria screen was positive for Plasmodium falciparum and she was commenced on quinine. On day 5 of her admission she developed perioral pares...

ea0005p37 | Clinical Case Reports | BES2003

A case of ectopic ACTH with severe opportunistic infection

Hatfield E , Pal S , Meeran K , Williams G , Todd J

A case of ectopic ACTH with severe opportunistic infectionECI Hatfield, S Pal, K Meeran, G Williams, JF Todd.Endocrine Unit, Imperial College, Hammersmith Hospital, London, UKA twenty six year old female presented with symptoms and signs suggestive of Cushing's Syndrome. Initial investigations showed hypokalaemia (potassium 2.3nmol/L), elevated urinary free cortisols, (3400, 18,000, 31,000 nmol/24 hour (NR <270)), diabetes (fasting glucose =9 mmol/L), loss of di...

ea0078p58 | Pituitary and Growth | BSPED2021

Management of cranial Diabetes Insipidus in a paediatric tertiary centre – clinical outcomes and patient perception of care

Garrahy Aoife , Dilrukshi MDSA , Vickars Marcus , Pal Aparna , Ryan Fiona , Makaya Taffy

There is growing recognition within Endocrinology physician and patient groups of morbidity and mortality in association with prescribing errors and dysnatraemia, in hospitalised patients with cranial diabetes insipidus (CDI). The study had two aims; firstly, to assess outcomes in hospitalised patients (paediatric and adult) with CDI by review of electronic records from 2012-2021, and secondly, to assess the same patient cohort’s perceptions of their care via telephone qu...

ea0081oc9.6 | Oral Communications 9: Environmental Endocrinology | ECE2022

Iodine nutrition among adolescent Faroese comply with recommendations – are we home-safe?

Johannesen Herborg Liggjasardottir , Andersen Stig , Nielsen Kari Rubek , Weihe Pal , Petersen Maria Skaalum , Veyhe Anna Sofia

Introduction: Iodine nutrition is critical for human health. In recent years the main focus was on the developing brain during pregnancy. In addition, iodine nutrition is essential for growth and development during adolescence. Iodine nutrition was recently low within the recommended range among adult Faroese living on local, iodine-rich marine food items. Dietary habits among young generations are drifting away from local foods, and this raises a concern that led us to perfor...

ea0081p21 | Adrenal and Cardiovascular Endocrinology | ECE2022

Time from referral to definitive treatment in Cushing’s syndrome

Coulden Amy , Aylwin Simon , Flanagan Daniel , Mamoojee Yaasir , Pal Aparna , Gittoes Neil , Gleeson Helena

Rapid diagnosis and treatment of Cushing’s syndrome (CS) is essential for good outcomes. Current standards for appropriate timelines for referral are under review by NHSE. Data are required to substantiate standard setting. Knowledge of current referral pathways/processes are required to explore delays in accessing definitive surgical treatment. An audit of referral processes at Queen Elizabeth Hospital Birmingham was undertaken and further expanded to 4 additional tertia...