Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0066in1.1 | (1) | BSPED2019

Cheetham Tim

Tim Cheetham is a University Reader and Honorary Consultant Paediatrician based in Newcastle-upon-Tyne, England, UK. He was appointed in 1996 following paediatric / endocrine / diabetes training in Oxford and Cambridge – and following 6 months as a neonatal consultant at Addenbrooke’s. He has a broad range of interests and has a key role in a number of clinical trials and studies in the field of clinical endocrinology including Graves’ disease, longer term outco...
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ea0051cme4 | CME Training Day Abstracts | BSPED2017

Thyrotoxicosis – diagnosis and management

Cheetham Tim

Key discussion points• Make sure you know what it is that you are treating – is this Graves’ hyperthyroidism (with associated TSH receptor antibodies) or simply a brief, hyperthyroid phase of autoimmune thyroid disease (without TSH receptor antibodies) that will settle down spontaneously?• Ideally obtain the result of the thyroid receptor antibody titre pre intervention with carbimazole.&#...
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ea0030s6 | CME TRAINING DAY | BSPED2012

Hyperthyroidism and its management

Cheetham Tim

Thyrotoxicosis is uncommon in young people with a UK incidence around 1/100 000 (<15 years). Most cases of persistent thyroid hormone excess are due to Graves’ disease although transient episodes are seen in Hashimoto’s thyroiditis. Thyroid peroxidase antibodies can frequently be identified in both forms of autoimmune thyroid disease with antibodies to the TSH receptor more typical of Graves’. Patients with Graves’ are usually managed initially with the...
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ea0019s24 | What is the TSH set point? Does it matter? | SFEBES2009

Abnormalities of the HPT axis – lessons from paediatric endocrinology

Cheetham T

The spectrum of thyroid problems seen in paediatric endocrine practice is different to that seen in later life. Topics that have attracted particular interest include the HPT axis in pre-term infants, the significance of a subtle increase in TSH, and associations between thyroid function in childhood and risk of disease in later life. This talk will include lessons learnt from patients seen in North–East England and from studies conducted in the same locality.<p class...
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ea0033p3 | (1) | BSPED2013

Diagnosing congenital adrenal hyperplasia. Radiologist rather than biochemist.

Schenk Daniel , Cheetham Tim

Introduction: The male child with congenital adrenal hyperplasia (CAH) due to 21 hydroxylase deficiency classically presents with salt-wasting and the female with genital ambiguity. 17-OHP measurement is a key investigation but the assay takes time to perform and is not usually available at weekends. We have examined the role of renal/adrenal ultrasonography in the above clinical scenarios.Method: An abdominal ultrasound focussing on adrenal anatomy was ...
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ea0027oc1.3 | Oral Communications 1 | BSPED2011

High likelihood of malignancy in patients presenting with a thyroid nodule

Jamil Furrukh , Cheetham Tim

Introduction: Thyroid nodules in children are more often malignant than in adult practice (~26 vs 5–10%) and in our locality the incidence of thyroid cancer in young people is increasing. We therefore assessed the presentation, investigation, histology and management of paediatric patients presenting with thyroid nodules.Methods: This was a retrospective audit conducted at a regional unit (catchment population ~3 million) where young people are like...
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ea0017p33 | (1) | BSPED2008

Pseudohypoparathyroidism: an evolving clinical and biochemical picture

Joshi S , Cheetham T

Introduction: Children with pseudohypoparathyroidism (PHP) can have a broad range of phenotypic features and biochemical abnormalities. The heterogeneity of this patient group prompted us to review the clinical features of these children in our service.Methods: We recorded the mode of presentation, clinical features, growth pattern, biochemical profile and progress of 13 paediatric patients with PHP and hypocalcaemia under review in our service over a 11...
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ea0039oc2.2 | Oral Communications 2 | BSPED2015

Inguinal hernia repair in a girl, a missed opportunity to diagnose 17β-HSD

Jamil Syed Furrukh , Cheetham Tim

17β-hydroxysteroid dehydrogenase deficiency (17β-HSD) is a rare autosomal recessive disorder of sexual development affecting testosterone biosynthesis. Affected individual typically present with genital ambiguity at birth, inguinal gonads or excessive virilisation at puberty in a phenotypic female.Case: We present a case of a 14-year-old girl who was referred by the GP because of concerns about upper lip hair growth and deepening of her voice. ...
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ea0051oc5.9 | Oral Communications 5 | BSPED2017

Adult height in patients with testotoxicosis

Lane Laura C , Flowers Josephine , Cheetham Timothy

Background: Familial male-limited precocious puberty (FMPP) or ‘testotoxicosis’ is a rare form of gonadotrophin-independent precocious puberty. There is a paucity of data on final adult height in these patients and no consensus on what constitutes appropriate treatment. Our aim was to assess the management and final height of patients with FMPP under our care as well as those reported in the literature.Methods: Growth data were obtained from no...
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ea0082wd5 | Workshop D: Disorders of the adrenal gland | SFEEU2022

Optimising the biochemical control in a young patient with classical Congenital Adrenal Hyperplasia (CAH) and history of azoospermia, resulted in spermatogenesis

Ali Mudassir , Cheetham Tim , Mitchell Anna

A male with classical salt-wasting congenital adrenal hyperplasia (CAH; 21-hydroxylase deficiency) who was diagnosed in infancy and had normal pubertal growth and development attended the endocrine department for routine follow up in June 2019 (age 26). His current daily medications are hydrocortisone 10 mg on waking, 5 mg at 4 pm and fludrocortisone 200 mg once daily. He also has injectable hydrocortisone sodium phosphate 100mg for emergency use. Over recent years, he reports...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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