Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1028 | Male Reproduction | ICEECE2012

Cyclooxygenase-1 (COX-1) and COX-2, differently expressed in human sperm from normal and pathological patients, might be considered molecular markers in the diagnosis of male infertility disorders

Perrotta I. , Santoro M. , Guido C. , Avena P. , Amicis F De , Cesario M. , Maris P. , Tripepi S. , Aquila S.

Varicocele and diabetes mellitus (DM) have long been recognized to impair male fertility by interfering with both sperm parameters and production, however the molecular mechanism by which these effects occur remains largely unknown. Cyclooxygenases are important in spermatogenesis, but their ultrastructural localization in sperm cells and their role in male infertility have not yet established in humans. In the present study we presented the evidence of constitutive (COX-1) an...