Endocrine Abstracts

Obesity has become one of the most important public health problems. Considered as one of the many adverse consequences of overweight and obesity, the maleobesity-associatedsecondary hypogonadism (MOSH) is a very prevalent and undervalued condition. Is characterized by low total testosterone (TT) levels associated to low or inappropriately normal luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Increased aromatase activity, imbalance in the testosterone/estradi...

Considered as the biggest public health problem, the pandemic growth of obesity is associated to decline of male fertility potential over the last 50 years. Thus far, the effect of weight loss on semen parameters is still controversial and poorly understood. In this study we report the effect of significant weight loss on semen parameters of two obese men with metabolic syndrome. The patients followed to a very low-calorie ketogenic diet (VLCKD) according to a commercial weigh...

Obesity is the single most significant risk factor for testosterone deficiency in men, with a reported prevalence up of 60% of male obesity secondary hypogonadism (MOSH). Several studies have shown that significant weight loss due to bariatric surgery have significant metabolic and endocrine improvement in obesity, however the results achieved with conventional diet and lifestyle change are poor and not able to reverse this condition. As an alternative to bariatric surgery, we...

Sao Paulo is the most populous city in Brazil and its huge number of vehicles contributes for a higher concentration of air pollutants that may interfere in human fertility. The aim of this study was to evaluate the influence of air pollution of vehicular origin on hormonal and seminal parameters of traffic controllers. Clinical history, physical examination (testicular volume, presence of varicocele, cryptorchidism, malformations), hormonal (estradiol, LH, FSH and total testo...